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10678

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Anthranilic acid

puriss. p.a., matrix substance for MALDI-MS, ≥99.0% (T)

Synonym:2-AA, 2-Aminobenzoic acid
CAS Number:118-92-3
Linear Formula:2-(H2N)C6H4CO2H
Molecular Weight:137.14
Beilstein Registry Number:471803
EC Number:204-287-5
MDL number:MFCD00007712
PubChem Substance ID:24846741

Description

ApplicationUsed for non-selective, efficient fluorescent labeling of glycans.
 Fluorescently labels glycans containing a free reducing terminus.1,2,3,4
Other NotesSales restrictions may apply

Properties

gradematrix substance for MALDI-MS
vapor density4.7 (vs air)
 puriss. p.a.
assay≥99.0% (T)
fluorescenceλex 315 nm; λem 400 nm(lit.)
mp144-148 °C(lit.)
 144-148 °C
cation tracesBa: ≤5 mg/kg
 Ca: ≤10 mg/kg
 Cd: ≤5 mg/kg
 Co: ≤5 mg/kg
 Cr: ≤5 mg/kg
 Cu: ≤5 mg/kg
 Fe: ≤20 mg/kg
 K: ≤50 mg/kg
 Mg: ≤5 mg/kg
 Mn: ≤5 mg/kg
 Na: ≤50 mg/kg
 Ni: ≤5 mg/kg
 Pb: ≤5 mg/kg
 Zn: ≤5 mg/kg
abs.absorption/337 nm ≥2000 (mol. absorption)

Safety

Personal Protective Equipmentdust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard CodesXi
Risk Statements36
Safety Statements26-36
WGK Germany2
RTECSCB2450000

Related Products

Related productPP0530, GlycoProfile™ 2-AA Labeling Kit

References

Cited Reference1. Bigge J.C., et al., , Nonselective and efficient fluorescent labeling of glycans using 2-amino benzamide and anthranilic acid. Anal. Biochem. 230, 229-238, (1995) Abstract
 2. Anumula, K.R., Quantitative determination of monosaccharides in glycoproteins by high-performance liquid chromatography with highly sensitive fluorescence detection. Anal. Biochem. 220, 275-283, (1994) Abstract
 3. Anumula, K.R. and Dhume, S.T., High resolution and high sensitivity methods for oligosaccharide mapping and characterization by normal phase high performance liquid chromatography following derivatization with highly fluorescent anthranilic acid. Glycobiology 8, 685-60, (1998)
 4. Kae Sato, L., et al., , Optimization of derivatization with 2-aminobenzoic acid for determination of monosaccharide composition by capillary electrophoresis. Anal. Biochem. 262, 195-197, (1998) Abstract
referenceHuang, Z., et al., The use of the 2-aminobenzoic acid tag for oligosaccharide gel electrophoresis. Carbohydr. Chem. 328, 77-83, (2000)
 He, L., et al., Separation of saccharides derivatized with 2-aminobenzoic acid by capillary electrophoresis and their structural consideration by nuclear magnetic resonance. Anal. Biochem. 314, 128-134, (2003)
 Neville, D.C., et al., Analysis of fluorescently labeled glycosphingolipid-derived oligosaccharides following ceramide glycanase digestion and anthranilic acid labeling. Anal. Biochem. 331, 275-282, (2004)
MerckMerck 13,421
BeilsteinBeil. 14,IV,1004
 Aldrich MSDS 1, 131:A / Corp MSDS 1 (1), 282:B / FT-IR 1 (2), 189:A / FT-IR 2 (2), 2651:B / FT-NMR 1 (2), 1066:B / IR-Spectra (2), 838:G / IR-Spectra (3), 958:B / NMR-Reference 2 (2), 186:B / RegBook 1 (2), 1783:N / Sax 6, 291 / Sigma FT-IR 1 (2), 291:B / Structure Index 1, 284:D:8